Among these receptors p2x 5 and p2x 6 and p2x 2 and p2x 5 have been found to be expressed in chick and rat skeletal muscle development respectively 5 11 on the contrary the expression and function of p2y nucleotide receptors in developing skeletal muscle cells has rarely been studied. Confocal calcium imaging reveals an ionotropic p2 nucleotide receptor in the paranodal membrane of rat schwann cells peter grafe christian mayer tomoko takigawa martin kamleiter the p2 nucleotide receptors totowa nj usa humana press 1998 pp 3 40. In the p2 nucleotide receptors leading researchers from major laboratories around the world summarize our current knowledge of the molecular biology the physiology and the pharmacology of the p2 receptors. Inhibition of a1 adenosine receptor by psb36 modulates the spinal antinociception in animal models psb36 is a very potent selective antagonist of the adenosine a1 receptor the compound selectivity ki for human a1 a2a a2b and a3 receptors is 07 980 187 and 2300 respectively
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