Pharmacokinetics pharmacodynamics and allometric scaling of chloroquine in a murine malaria model brioni r moore 1 madhu page sharp 1 jillian r stoney 1 kenneth f ilett 2 3 jeffrey d jago 4 5 and kevin t batty 1 5 . Mahmood i prediction of drug clearance in children from adult clearance allometric scaling versus exponent 075 in pharmacokinetic allometric scaling in pediatric drug development rockville pine house publishers 2013 p 41 55 google scholar. Pediatric drug development has been hampered by the cost of developing new formulation ethical constraints to drawing blood and other practical difficulties paving the way for voluntary pediatric drug assessments allometric scaling population pharmacokinetics poppk modeling or physiologically based pharmacokinetic pbpk . Please note my recent book entitled pharmacokinetic allometric scaling in pediatric drug development this book mainly emphasizes on the prediction of pk parameters in pre term and term neonates infants and toddlers from adult data this book will be helpful to clinical pharmacologists pharmacometricians and the pediatric researchers. He is author of the books interspecies pharmacokinetic scaling pediatric pharmacology and pharmacokinetics and pharmacokinetic allometric scaling in pediatric drug development dr
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