Chapter 10 operationalization of global alzheimers disease trials challenges and opportunities seen with global alzheimers clinical trials1031 see biomarkers involved and there can be a range of scales used at varying time points over the lifespan of the trial 1033 disease modifying drugs. 10 factors to consider for your alzheimers disease clinical trial to help make a global trial become a feasible effective answer to patient enrollment global alzheimers disease trials 10 factors to consider. Global clinical trials for alzheimers disease is a handy one stop reference for researchers and physicians planning and conducting global clinical trials in this area this book addresses important considerations that may arise during the successful design and execution of these trials including site selection local regulatory issues pharmacogenomics ethical matters and much more. Alzheimers disease ad therapies are increasingly being tested in global clinical trials a search of clincaltrialsgov revealed that of 269 currently active trials 28 are currently being conducted in the united states the majority of trials and the majority of trial sites are ex us. Latinos and african americans at risk research shows that older latinos are about one and a half times as likely as older whites to have alzheimers and other dementias while older african americans are about twice as likely to have the disease as older whites
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